CAS 28537-70-4 | BMB Crosslinker | CHEMSOON-Cross linkers professional supplier

Product Name：Tetramethylenedimaleimide
Synonymous：BMB Crosslinker;1,1'-(1,4-Butanediyl)bis[1H-pyrrole-2,5-dione]; 1,4-Bis(maleimide)butane; 1,4-Bis(maleimido)butane; 1,4-Di(maleimido)butane; 1-[4-(2,5-Dioxopyrrol-1-yl)butyl]pyrrole-2,5-dione; N,N'-1,4-Butylenebismaleimide; N,N'-Tetramethylenebis[maleimide]; N,N'-Tetramethylenedimaleimide; Tetramethylenebismaleimide;
CAS：28537-70-4

Basic Info

M.F.	C12H12N2O4		M.W.	248.23468
Appearance

Properties

1) It is soluble in DMF and DMSO
2) Sealed at room temperature

Appications

1) It can be used as crosslinking agent

Characterization

HNMR

FTIR

HPLC

Reference

1) Feast, William J.; Put, J.; De Schryver, F. C.; Compernolle, F. C.; Organic Mass Spectrometry 1970, 3(4), 507-517, DOI: 10.1002/oms.1210030408 ; Mass spectra of maleimides, isomaleimides, bis-maleimides, bis-isomaleimides and the intramolecular photocyclization products of bis-maleimides

2) Matuszak, Nicolas; Muccioli, Giulio G.; Labar, Geoffray; Lambert, Didier M.; J. Med. Chem. 2009, 52(23), 7410-7420, DOI: 10.1021/jm900461w ; Synthesis and in Vitro Evaluation of N-Substituted Maleimide Derivatives as Selective Monoglyceride Lipase Inhibitors

3) Green, Nora S.; Reisler, Emil; Houk, K. N.; Protein Science 2001, 10(7), 1293-1304, DOI: 10.1110/ps.51201 ; Quantitative evaluation of the lengths of homobifunctional protein cross-linking reagents used as molecular rulers

4) Cheronis, John C.; Whalley, Eric T.; Nguyen, Khe T.; Eubanks, Shad R.; Allen, Lisa G.; Duggan, Matthew J.; Loy, Sharon D.; Bonham, Kathryn A.; Blodgett, James K.; J. Med. Chem. 1992, 35(9), 1563-1572, DOI: 10.1021/jm00087a010 ; A new class of bradykinin antagonists: synthesis and in vitro activity of bissuccinimidoalkane peptide dimers