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Product: CeO₂@ZIF-8
Synonyms: NA
CAS：NA
Basic Information
| Unit MF. | NA | Unit MW. | NA | ||
| Coordination Metal | Zn | Linkers |
2-methylimidazole (2-MI) |
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| Pore Size | NA | Pore volume | NA | ||
| Surface Area | NA | ||||
| Analog Structure | NA | ||||
Product Property
| Appearance | Off-white powders | |||
| Particle Size | ~200nm | |||
Stability
1) Stable in water solution;
2) unstable in PBS (pH7.4) buffer and slowly decomposes;
3) remains stable even after 48-hour incubation in DMEM with 10% fetal bovine serum (FBS).
4) Thermal stable at 400℃
Preservation
1) Keep in a dry and cool place, sealed.
2) Directly put into utility without special activation
Other Features
Fluorescence: NA;
Applications
1) With high antioxidant activity, CeO2@ZIF-8 can effectively scavenge various reactive oxygen species (ROS), such as superoxide anion, hydrogen peroxide, and hydroxyl radical;
2) ZIF-8 encapsulation can regulate the size, shape, and surface charge of CeO2 to make it more suitable for biological applications;
3) ZIF-8 can decompose in acidic environments (such as tumor tissues and acidic organelles) to release active components..
Characterizations
References
1) He, Lizhen; Huang, Guanning; Liu, Hongxing; Sang, Chengcheng; Liu, Xinxin; Chen, Tianfeng; Science Advances, 2020, 6(12), eaay9751, DOI: 10.1126/sciadv.aay9751, Highly bioactive zeolitic imidazolate framework-8–capped nanotherapeutics for efficient reversal of reperfusion-induced injury in ischemic stroke